Some pet shops are very reliable and have a good knowledge of guinea pigs, although unfortunately it seems that many pet shops currently don't have the knowledge they should. Therefore it's a good idea for you to be clued up before you make a purchase.
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Observe the general health of the guinea pigs
The guinea pigs should be of a healthy weight and the body should be tube-shaped or even a slight pear shape. If the torso becomes sunken before reaching the hind legs, the guinea pig is probably underweight.
Observe the coat for bald patches or signs of a skin problem. The coat should be thick and shiny with no bald patches or skin flakes.
There should be no discharge from the nose or mouth, the ears should be clean, and the eyes should be bright.
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Check the sale pen for cleanliness and basic essentials
Are the animals well cared for by the pet shop? Is the pen clean? Do the animals have hay, feed and water in easy reach?
Ask to see the sex of the guinea pig
Have the staff pick up the guinea pig and show you the sex. Pet shops can mistake one for the other and sometimes, in the case of mistaking a male for a female, this can end up in an unplanned pregnancy if you have been sold "two females". This happened to me before I knew how to sex a guinea pig, but fortunately I noticed the mistake before the female had become pregnant. Take a look at our guide to sexing a guinea pig and teach yourself how to do it!
Decline offers to sell you a rabbit companion
Many people have had rabbits and guinea pigs happily living together for years. However, there are particular physical risks to the guinea pigs, so new rabbit and guinea pig pairings are discouraged.
Rabbits and guinea pigs have different dietary requirements and therefore require different dried food. Dried guinea pig feed contains Vitamin C, but dried rabbit feed does not. Guinea pigs require Vitamin C in their diet. I have also heard rumours that rabbit feed manufacturers add rabbit antibiotics to the feed which can be harmful to guinea pigs.
Guinea pigs are tube shaped and low to the ground. This means every important part of their anatomy is vulnerable. A kick from an excited rabbit can cause injury and because of their shape, a kick to any part of the guinea pig can be serious.
For both rabbits and guinea pigs, the company of their own species is far better than the company of another. I know little about rabbits, but guinea pigs are certainly very social and the company of another guinea pig is almost a requirement for most.